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[胸壁的差异化突肉瘤与形状的特征]

Aranza Odeth Canchola-Ibarra¹, Carlos Ortiz-Hidalgo²

¹Departamento de Anatomía Patológica, Fundación Clínica Médica Sur, Ciudad de México, México.

Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia

|July 7, 2023

概括

这份病例报告详细介绍了一种罕见的差差分化的突肉瘤 (SS) 与一个33岁的妇女的形状特征. 通过免疫组织化学和SS18基因重排证实了诊断,突出显示了它的攻击性.

科学领域:

在瘤学瘤学.
病理学病理学病理学
遗传学是一个遗传学.

背景情况:

突肉瘤 (SS) 是一种罕见的软组织肉瘤.
在突肉瘤中,形状的特征并不常见,这表明潜在的更具侵略性的亚型.
准确的诊断对于适当的患者管理至关重要.

研究的目的:

报告一个罕见的差差分化的突肉瘤与rhabdoid特征的病例.
描述这种罕见实体的临床,放射和病理发现.
为有限的关于带有形形态的突肉瘤的文献做出贡献.

主要方法:

磁共振成像 (MRI) 用于瘤评估.
细胞形态的组织病理学检查.
针对特定蛋白质标记物的免疫组织化学研究 (TLE1,Bcl-2,EMA,CAM5.2,CD138,CD56,desmin,SMA,S100).
光现场杂交 (FISH) 用于SS18基因重组.

主要成果:

一名33岁的妇女出现了胸壁瘤,侵入了多个相邻结构.
组织病理学揭示了具有形形态的小/中细胞片.
免疫组织化学显示TLE1,Bcl-2,EMA,CAM5.2,CD138和CD56的阳性.
鱼类证实了SS18基因重组.
确立了差差分化的SS与rhabdoid特征的诊断.

结论:

这代表了第八个报告的带有形特征的突肉瘤病例.
差异化SS与rhabdoid特征是一个罕见的和积极的瘤.
包括免疫组织化学和遗传分析在内的综合诊断方法对于诊断至关重要.

关键词:

在现场混合.在现场混合化.修订条例 SS18 修订条例在SS18中进行重排.这种类型的肉瘤是阴道肉瘤.突肉瘤 (Synovial Sarcoma) 是一个突肉瘤.这些瘤是拉布多伊德瘤.具有形状特征的瘤.

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