血清维生素D与牙周病的关联
Ying Li1, Jinjuan Wang2, Yunxian Cai1
1Department of Health Management Center, Hangzhou Fuyang Hospital of Orthopedics of Traditional Chinese Medicine, Hangzhou, China.
International dental journal
|July 7, 2023
概括
较高的维生素D水平可能会预防牙周病. 这项大型的日本研究发现了显著的关联,与增强树模型显示预测疾病发病的承诺.
科学领域:
- 营养生物化学 营养生物化学
- 牙周病学 牙周病学
- 公共卫生 公共卫生
背景情况:
- 关于维生素D与牙周病之间的联系,存在相互矛盾的证据.
- 血清25(OH) D3是维生素D状态的关键指标.
- 牙周病是一个重大的公共卫生挑战.
研究的目的:
- 为了研究血清25(OH) D3水平与牙周病在日本大人口中的关联.
- 探索维生素D对牙周病的潜在保护作用.
- 评估用于预测牙周病发病的机器学习模型.
主要方法:
- 分析了日本2009-2018年国家健康和营养检查调查 (NHANES) 的数据 (n=23,324).
- 使用后勤回归模型来评估血清维生素D与牙周病之间的关系,控制各种人口和健康因素.
- 机器学习算法 (提升树,人工神经网络,AdaBoost,随机森林) 用于预测建模.
主要成果:
- 血清维生素D被发现与牙周病有负面关联 (P趋势<0.05).
- 与最低四分之一 (Q1) 相比,较高的维生素D水平 (Q2-Q4) 显示牙周病的几率降低.
- 维生素D的保护作用在60岁以下的女性中更为明显. 一个提升树模型展示了良好的预测准确性.
结论:
- 维生素D可以作为预防牙周病的保护因素.
- 机器学习,特别是提升树算法,显示出预测牙周病风险的潜力.
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