肺癌手术后与心房相关的危险因素:一个多中心病例控制研究
Lifu Zhang1, Xinv Li2, Haifeng Wu3
1ECG Room, Jiangxi Cancer Hospital, The Second Affiliated Hospital of Nanchang Medical College, Jiangxi Clinical Research Center for Cancer, Nanchang, 330029, China.
Asian journal of surgery
|July 7, 2023
概括
肺癌手术后的术后心房 (POAF) 与手术前大脑类型尿素 (BNP) 水平和白细胞 (WBC) 数量较高有关. 男性性别,淋巴结解剖和心血管疾病也会增加POAF风险.
科学领域:
- 心脏病学 心脏病学
- 胸部外科手术 胸部外科手术
- 在瘤学瘤学.
背景情况:
- 手术后心房动 (POAF) 是经过重大胸部手术后的常见并发症.
- 在肺癌患者中确定POAF风险因素对于改善结果至关重要.
研究的目的:
- 在接受肺癌手术的患者中调查与POAF相关的风险因素.
主要方法:
- 一项涉及3家医院216名肺癌患者的病例控制研究 (2020年5月至2022年5月).
- 患者被分为POAF (病例) 和无POAF (对照) 组.
- 用单变量和多变量逻辑回归分析来确定风险因素.
主要成果:
- 对POAF的显著风险因素包括手术前脑型尿素 (BNP) 水平升高 (OR:4.46),男性性别 (OR:0.07),手术前白细胞 (WBC) 数量增加 (OR:3.00),淋巴结剖析 (OR:11.49) 和心血管疾病 (OR:4.93).
结论:
- 手术前的BNP水平,性别,手术前的白细胞计数,淋巴结解剖,以及心血管疾病史 (高血压,冠心病,心肌梗塞) 与肺癌手术后的POAF风险增加显著相关.
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