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在喘中测量的高亡性内皮微粒水平,具有高的IgE和eosinophils
Yael Strulovici-Barel1, Robert J Kaner1,2, Ronald G Crystal3,4
1Department of Genetic Medicine, Weill Cornell Medicine, 1300 York Avenue, Box 164, New York, NY, 10065, USA.
Respiratory research
|July 7, 2023
概括
过敏性喘患者具有高IgE和乙氨基基基的IgE和乙氨基基基的IgE和乙氨基基基的IgE和乙氨基基基的IgE和乙氨基基基的IgE和乙氨基基基的IgE和乙氨基基的IgE和乙氨基的IgE和乙氨基的IgE显示出更多的apoptotic内皮微粒 (EMP). 这表明EMP可能表明特定喘亚型的内皮功能障碍,有助于精确治疗的开发.
科学领域:
- 肺部医学 肺部医学
- 血管生物学 血管生物学
- 免疫学 免疫学 免疫学
背景情况:
- 喘传统上被视为呼吸道上皮质和光滑肌肉疾病.
- 新出现的证据表明,一些喘患者的呼吸道毛细体内皮功能障碍,血管重塑和血管生成.
- 喘中的炎症分为2型高 (eosinophilic) 或2型低 (neutrophilic/pauci-granulocytic) 的类型.
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