发展神经血管与年龄相关的黄斑变性的第二眼有较少的症状和更好的一年视觉结果
F Sema Akkan Aydoğmuş1,2, Oluchukwu Onwuka2,3, Jackson Saddemi2,4
1Ophthalmology Department, Ankara Sehir Hastanesi, Üniversiteler, Çankaya, Ankara, Turkey.
BMC ophthalmology
|July 7, 2023
概括
被诊断为神经血管年龄相关黄斑变性 (nAMD) 的第二眼比第一眼显示出更好的视觉敏度和更小的色素上皮质脱落 (PED) 高度. 这表明监测可以在连续的nAMD病例中提前诊断和改善结果.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 斑点退化症 斑点退化症
背景情况:
- 神经血管与年龄相关的黄斑变性 (nAMD) 影响了连续的眼睛.
- 了解顺序性nAMD的结果对于患者管理至关重要.
研究的目的:
- 为了比较被诊断患有nAMD的第一眼和第二眼之间的视觉和解剖结果.
- 评估诊断时的结果和治疗后的一年.
主要方法:
- 回顾52名患有顺序性nAMD的患者的病例系列.
- 治疗包括注射抗血管内皮生长因子 (抗VEGF).
- 测量结果包括视敏度 (VA),中央黄斑厚度 (CMT) 和通过光学连贯断层扫描 (OCT) 的颜色上皮质脱落 (PED) 高度.
主要成果:
- 与第一眼相比,第二眼在诊断时有更好的VA (logMAR 0.41vs. 0.68) 和一年 (logMAR 0.42vs. 0.61).
- 在诊断时 (225微米对155微米) 和一年 (188微米对140微米) 的第一眼显示出更高的PED高度.
- 与第一眼 (71.2%) 相比,第二眼的症状较少 (28.8%),症状形状不同.
结论:
- 患有nAMD的第二眼通常比第一眼具有更好的视力和较小的PED高度.
- 监测可能有助于在第二眼中更早诊断nAMD,从而改善结果.
- 这些发现强调了对顺序的nAMD发展进行警监测的重要性.
关键词:
抗血管内皮生长因子 抗血管内皮生长因子冠状腺新血管化疗法同胞眼中的眼睛.神经血管与年龄相关的黄斑变性.光学连贯性断层扫描技术.视网膜色素上皮质脱落 脱落风险因素 风险因素视力敏度 视力敏度 视力敏度更多相关视频
10:24Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
10.2K
05:14Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
Published on: August 11, 2023
1.1K
相关概念视频
01:27Open Angle Glaucoma: Treatment
481
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
481
01:25Glaucoma: Overview
629
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
629
01:28Angle Closure Glaucoma: Treatment
575
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
575
01:22Photoreceptors and Visual Pathways
6.1K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.1K