合成和杀虫活性研究含有二罗烯乙衍生物的阿齐多皮里德
Shao-Meng Zhou1, Zhen-Yu Wang1, Xiao-Hui Zhu1
1National Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensor Technology and Health, Central China Normal University, Wuhan 430079, P. R. China.
Journal of agricultural and food chemistry
|July 8, 2023
概括
基于pyridalyl的新型杀虫剂衍生品显示出对关键农业害虫的提高有效性. 中间基链的修改导致具有优越杀虫活性的化合物,为害虫控制提供了有希望的替代品.
科学领域:
- 农业化学 农业化学
- 有机合成 有机合成
- 杀虫剂开发 杀虫剂开发
背景情况:
- 皮里达利 (Pyridalyl) 是一种新型杀虫剂,对虫幼虫和虫具有广泛的疗效.
- 以前的研究重点是修改pyridalyl的pyridine部分,对其他结构组件的探索有限.
研究的目的:
- 为了合成和评估新型含有阿齐多皮里德的二罗乙烯衍生物.
- 为了研究修改后的化化合物的杀虫活性,准中间基链.
主要方法:
- 一系列新型二醇乙烯衍生物的合成.
- 对合成的化合物进行查,以检测它们对*Plutella xylostella*的杀虫活性.
- 在实验室和实地试验中对各种Lepidoptera害虫的疗效进行比较分析.
主要成果:
- 合成的化合物对*P. xylostella*表现出中度至高的杀虫活性.
- 化合物III-10在较低的LC50值 (0.831毫克L-1) 与pyridalyl (2.021毫克L-1) 相比,显示出更高的疗效.
- 化合物III-10显示出广泛的杀虫剂光谱,并提高了对*Chilo suppressalis*的现场控制效率.
结论:
- 修改pyridalyl的中间基链是一种可行的策略,用于开发强大的杀虫剂.
- 化合物III-10代表了下一代杀虫剂具有增强效力的有希望的领先地位.
- 对结构-活性关系的进一步研究可以优化杀虫剂特性.
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