在寒冷大气等离子体周围的细菌抑制和耐受性机制
Hao Zhang1, Chengxi Zhang1, Qi Han2
1State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Disease, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, People's Republic of China.
Applied microbiology and biotechnology
|July 8, 2023
概括
冷大气等离子体 (CAP) 提供了一种新的方法来对抗细菌感染,特别是耐药菌株. 本综述详细介绍了农业政策的细节.
科学领域:
- 微生物学与传染病的研究
- 等离子体物理学和化学等离子体物理学和化学
- 生物医学工程 生物医学工程
背景情况:
- 抗生素耐药性对全球健康构成重大威胁,需要使用替代抗菌战略.
- 冷大气等离子体 (CAP) 由于其多样化的反应性物种,具有强大的抗微生物特性.
- 目前尚不完全了解CAP杀菌作用和细菌反应的确切机制.
研究的目的:
- 系统地审查和阐明CAP消灭细菌的机制.
- 讨论针对CAP治疗的细菌耐受性机制.
- 突出了CAP在细菌消毒方面的最新进展.
主要方法:
- 对研究CAP-细菌相互作用的研究进行系统文献综述.
- 细菌反应的分析,包括耐受性和生存机制.
- 汇编了CAP在杀菌环境中的近期应用.
主要成果:
- 农业农产品展示了杀死细菌的复杂和多方面的机制.
- 观察到对CAP的细菌耐受性,具有明显的潜在机制,需要进一步调查.
- CAP显示出卓越的疗效,特别是与其他消毒剂结合使用时.
结论:
- 冷大气等离子体为细菌感染控制提供了一个有希望的,非抗生素的战略.
- 了解CAP的杀菌和细菌耐受机制对于优化其治疗应用至关重要.
- 对尚未发现的耐受性机制的进一步研究可能会提高CAP对抗弹性细菌的有效性.
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