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在中度至重度初级开角青光眼患者中,Hemi-GATT与发泡化相结合:两年后的结果

Sunil Ruparelia¹, Darcie Wilson², Nir Shoham-Hazon^2,3

¹Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. sunil.ruparelia@dal.ca.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

|July 8, 2023

概括

下半球180°阴视镜辅助的透光干切除术 (hemi-GATT) 结合发泡乳化显示出适度至严重的初级开角玻璃眼 (POAG) 的良好结果. 这种手术方法有效降低眼内压力,并发症率低.

科学领域:

眼科医生眼科眼科
玻璃眼的手术玻璃眼的手术
最少侵入性玻璃眼外科手术

背景情况:

主要开角青光眼 (POAG) 是不可逆转失明的主要原因.
管理中度至严重的POAG通常需要有效的手术干预来降低眼内压力 (IOP).
阴视镜辅助的透光轨道切除术 (GATT) 是一种治疗青光眼的内部治疗方法.

研究的目的:

为了评估下半球180°阴影镜辅助透光轨道切除术 (hemi-GATT) 在中度至严重的初级开角玻璃眼 (POAG) 患者的结果.
为了评估外科手术成功率,眼内压力 (IOP) 降低,以及结合 hemi-GATT 和化后的并发症概况.

主要方法:

追溯性,单中心研究,包括112名中度至重度POAG患者的112只眼睛,这些患者接受了相结合的下半导体-GATT和发酵乳化.
手术成功被定义为两个标准:标准A (IOP<17 mmHg和>20%的减少) 和标准B (IOP<12 mmHg和>20%的减少).
结果措施包括IOP,局部IOP降低滴,最佳校正视敏度 (BCVA),视野平均偏差 (MD),以及91名患者24个月随访期间的并发症.

主要成果:

24个月后,卡普兰-梅尔分析显示,完全成功的概率为64.8% (标准A),合格成功的概率为93.4%.
在24个月内,眼内压力从基线 (21.9 ± 5.8 mmHg) 降低了37.9%,至13.6 ± 3.9 mmHg.
最常见的并发症是短暂的低血热 (25.9%),自发消失.

结论:

结合较低的Hemi-GATT与发泡乳化表明,中度至重的POAG患者的手术结果良好,并发症率低.
该程序实现了显著的IOP降低和高的成功率,过渡性低血是主要的不良事件.
需要进行进一步的比较研究,以评估 hemi-GATT 与 360° GATT 方法的对比.

关键词:

眼光障碍症是什么眼光障碍症是什么通过阴视镜辅助的透光轨道瘤切除术.这就是MIGS.主要的开放角光眼.

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