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Updated: Jul 24, 2025

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盖菲提尼布衍生物和耐药性:从分子动力学模拟的角度来看

A Ahmadi1, E Mohammadnejadi1, N Razzaghi-Asl2

  • 1Students Research Committee, School of Pharmacy, Ardabil University of Medical Sciences, Ardabil, Iran.

Computers in biology and medicine
|July 8, 2023
PubMed
概括

研究人员设计了新的gefitinib化合物,以克服表皮生长因子受体 (EGFR) 突变癌症的耐药性. 分子模拟确定了一个有前途的化合物,分子23,显示稳定的结合常见的EGFR突变,帮助未来的药物开发.

关键词:
在 DFT 方面,它是最重要的.盖菲提尼布 (Gefitinib) 是一种药物.分子动力学分子动力学在NSCLCLC中,我们可以看到.这就是为什么SAR SAR SAR.

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