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通过依赖于UPR的AMPK相关酶NUAK2进行增强的SARS-CoV-2进入

Vibhu Prasad1, Berati Cerikan1, Yannick Stahl1

  • 1Heidelberg University, Medical Faculty Heidelberg, Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Disease Research, Heidelberg, Germany.

Molecular cell
|July 8, 2023
PubMed
概括

严重急性呼吸道综合征冠状病毒-2 (SARS-CoV-2) 感染激活了IRE1α-XBP1通路,揭示了NUAK2作为关键宿主因素. NUAK2对于病毒进入和通过调节细胞表面病毒受体传播至关重要.

关键词:
在ACE2中,ACE2是ACE2.这就是Clem Clem.一个超结构的 IRE1a.这就是SARS-CoV-2病毒.这就是TMPRSS2的原因.冠状病毒冠状病毒病毒膜动力学 膜动力学走私和贩运的人口贩运不折叠的蛋白质反应反应病毒进入病毒的入口

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