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Updated: Jul 24, 2025

High-throughput Confocal Imaging of Quantum Dot-Conjugated SARS-CoV-2 Spike Trimers to Track Binding and Endocytosis in HEK293T Cells
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TMEM106B 是一个受体介导ACE2-独立的SARS-CoV-2细胞入口

Jim Baggen1, Maarten Jacquemyn1, Leentje Persoons1

  • 1KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven 3000, Belgium.

Cell
|July 8, 2023
PubMed
概括

研究人员发现TMEM106B作为SARS-CoV-2进入缺乏ACE2的细胞的替代受体. 这一发现揭示了SARS-CoV-2感染的新机制和潜在的治疗点.

关键词:
独立于ACE2的条目冠状病毒TMEM106B 其他TMEM106B 晶体结构抗体中和冠状病毒化电磁场输入接收器

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