调节IL-33/ST2信号传递作为潜在的心血管疾病的新治疗点

Punniyakoti Veeraveedu Thanikachalam1, Srinivasan Ramamurthy2, Poojitha Mallapu3

  • 1Department of Pharmaceutical Chemistry, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India.

概括

介素-33 (IL-33) 通过诱导保护性Th2细胞因子,保护心血管疾病 (CVD). 然而,可溶性ST2 (sST2) 会加剧心血管疾病,这表明IL-33是治疗点,sST2是诊断生物标志物.

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