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Updated: Jul 24, 2025

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快速查SARS-CoV-2变种,是流行病监测的一个关键工具

Irene Muñoz-Gallego1,2, María Ángeles Meléndez Carmona3,4, Carmen Martín Higuera3,4

  • 1Laboratory of Virology, Microbiology Department, Hospital Universitario, 12 de Octubre, Avda de Córdoba s/n, 28041, Madrid, Spain. iremunozg@gmail.com.

Scientific reports
|July 8, 2023
PubMed
概括

反转录聚合酶链反应 (RT-PCR) 有效分析严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 变体,没有显示与全基因组测序的差异. RT-PCR是对变种监测的一个有价值的工具,特别是在COVID-19发病率高的时候.

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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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