自动机器学习 (AutoML) 可以预测癌症胃切除术后的90天死亡率
Gopika SenthilKumar1,2, Sharadhi Madhusudhana2, Madelyn Flitcroft2
1Medical Scientist Training Program, Medical College of Wisconsin, Milwaukee, USA.
Scientific reports
|July 8, 2023
概括
自动机器学习 (AutoML) 有效地预测胃癌手术后的90天死亡率. 关键因素包括年龄,节点比率和住院时间,有助于术前风险评估.
科学领域:
- 在瘤学瘤学.
- 医疗信息学 医疗信息学
- 手术瘤学手术瘤学
背景情况:
- 预测早期的术后死亡率对于胃癌患者的管理至关重要.
- 胃癌手术 (胃切除术) 具有重大风险,需要仔细的手术前评估.
研究的目的:
- 用自动机器学习 (AutoML) 来预测经过胃切除术的胃癌患者的90天死亡率.
- 优化手术前预测模型,并确定有影响力的风险因素.
- 评估AutoML在外科瘤学中的实用性.
主要方法:
- 利用国家癌症数据库 (2004-2016) 进行胃切除术的I-III期胃癌患者.
- 训练有素的预测模型使用H2O.ai AutoML与26个功能.
- 在验证队列中使用曲线下的面积 (AUC) 评估模型性能.
主要成果:
- 性能最高的组合模型实现了0.77.7的AUC.
- 高龄,结节比率和住院时间 (LOS) 是最有影响力的预测因素.
- 结合预测节点比率或LOS的术前预测模型实现了0.73-0.74.7的AUC.
结论:
- 自动ML在预测胃切除术后胃癌患者90天死亡率方面表现强.
- 这些模型可以在手术前使用,以告知患者的预后和外科选择.
- 自动ML有可能在指导外科瘤护理方面得到更广泛的应用.
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