大麻使用频率与PrEP停止和自我报告的HIV诊断有关
Ethan Morgan1,2, Lisa A Eaton3, Ryan J Watson3
1College of Nursing, The Ohio State University, Columbus, OH, USA. morgan.1691@osu.edu.
AIDS and behavior
|July 8, 2023
概括
大麻使用与性少数群体男性和性别多样性个体中更高的暴露前预防 (PrEP) 停止率有关. 这一发现凸显了这一群体中艾滋病毒诊断的潜在风险因素.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 药物使用研究研究 药物使用研究
背景情况:
- 为了实现美国的"到2030年结束艾滋病毒流行"倡议,需要减少暴露前预防 (PrEP) 停止率.
- 大麻的非刑事化正在增加,特别是在性少数群体男性和性别多样性 (SMMGD) 个人中,需要了解其对PrEP使用的影响.
研究的目的:
- 在黑人和西班牙裔/拉丁裔SMMGD个体中调查大麻使用频率与PrEP停止之间的关联.
- 评估大麻使用模式,最近使用PrEP和该人口中的艾滋病毒状况之间的关系.
主要方法:
- 利用来自黑人和西班牙裔/拉丁裔SMMGD个人的全国研究的基线数据.
- 使用调整后的回归模型来分析过去3个月大麻使用频率与PrEP使用,最后一次PrEP剂量的近期和艾滋病毒状况之间的关联.
主要成果:
- 与非使用者相比,使用大麻一次或两次,每月或每周或更频繁的个人显示PrEP停止的几率明显更高.
- 大麻使用者也更有可能报告最近停止PrEP,其几率比率分别为0.11和0.14用于1-2次和每周或更频繁的使用.
结论:
- 在不同频率下,大麻使用与PrEP停止的增加以及SMMGD个体最近的停止有关.
- 调查结果表明,大麻使用者可能代表着艾滋病毒诊断风险较高的人群,因此需要进一步对具有全国代表性的样本进行调查.
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