儿童多系统炎症综合征 (MIS-C) 后高血压
Jake R Lehman1, Matthew Schuchman2, Elizabeth Mitchell3,4
1Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Pediatric nephrology (Berlin, Germany)
|July 8, 2023
概括
儿童多系统炎症综合征 (MIS-C) 可以导致高血压和住院后血压升高. 较高的BMI和急性损伤增加了这种风险,需要对受影响儿童进行仔细监测和潜在的治疗.
科学领域:
- 儿科 儿科 儿科
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
背景情况:
- 儿童多系统炎症综合征 (MIS-C) 是一种与SARS-CoV-2相关的严重疾病.
- MIS-C的长期健康影响,特别是心血管影响,尚不清楚.
研究的目的:
- 为了确定高血压 (HTN) 和高血压 (BP) 在MIS-C.之后的儿童的患病率.
- 确定与HTN和高血压后MIS-C发展相关的临床预测因素.
主要方法:
- 一项回顾性研究分析了63名被诊断为MIS-C的儿童的数据.
- 血压的分类是使用2017年美国儿科学会指导方针.
- 统计分析包括后勤回归来确定HTN和高血压的预测因素.
主要成果:
- 14%的儿童患有HTN,4%的儿童在住院后30天以上患有高血压.
- 增加的BMI z分数,急性损伤 (AKI),血清肌素峰值和最大CRP水平与MIS-C后更高的BP相关.
- 在住院期间,左心室缩症在46%的患者中被观察到,在随访时降至10%.
结论:
- 高血压和高血压是MIS-C的潜在长期并发症.
- 体重指数较高或有AKI病史的儿童患MIS-C后HTN的风险增加.
- 建议密切监测血压,并考虑服用抗高血压药物的儿童从MIS-C.康复.
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