对儿科术后肺静脉狭窄症的干预措施的结果和风险因素
Kristin T Fujita1, Michael P DiLorenzo2, Usha S Krishnan2
1Division of Pediatric Cardiology, Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons and New York-Presbyterian, New York, NY, USA. ko2464@cumc.columbia.edu.
Pediatric cardiology
|July 9, 2023
概括
在手术后的儿科肺静脉狭窄 (PVS) 的结果很差. 死亡率与复杂的先天性心脏病和遗传性疾病有关,而重复干预可以改善PVS患者的生存率.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 生产性心脏手术 手术 生产心脏手术
- 干预心脏病学 干预心脏病学
背景情况:
- 儿童肺静脉狭窄 (PVS) 是为先天性心脏缺陷进行手术后的一种严重并发症.
- 术后PVS的结果数据有限,特别是在异常肺静脉回归 (APVR) 修复后.
研究的目的:
- 审查一个单一中心的经验与儿科手术后PVS.
- 在这个患者群体中评估手术和透导管干预结果.
主要方法:
- 在2005年至2020年期间,在初始肺静脉手术后发展了复原症的儿科患者 (<18岁) 的回顾性研究.
- 纳入标准要求对手术后的PVS进行额外的干预.
- 审查的数据包括非侵入性成像,导管和手术记录.
主要成果:
- 确定了46名手术后PVS患者,11名 (23.9%) 死亡. 静脉缩发生在50%的患者中.
- 死亡率与单心室生理学,复杂先天性心脏病 (CCHD) 和遗传性疾病有关.
- 在APVR患者和接受三次或更多干预的患者中,生存率更高.
结论:
- 儿科手术后PVS的死亡率与诸如心血管疾病和遗传性疾病等特定的并发症有关.
- 静脉缩与包括男性性别和死性肠球炎在内的因素有关.
- 重复干预可能对生存有益,但需要进一步的研究.
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