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结直肠全厚内镜切除:系统性审查和元分析

Zaheer Nabi¹, Jayanta Samanta², Jahnvi Dhar²

¹Department of Interventional Endoscopy, Asian Institute of Gastroenterology, Hyderabad, India.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society

|July 9, 2023

概括

设备辅助内镜全厚切除 (EFTR) 是一种安全有效的结直肠病变治疗方法. 这一系统性审查发现EFTR在结肠和直肠中的成功率很高,并发症率很低.

科学领域:

胃肠病学胃肠病学
手术瘤学手术瘤学
内視鏡外科手術內視鏡外科手術

背景情况:

内镜全厚切除 (EFTR) 是一种正在发展中的结直肠病变的技术.
评估设备辅助EFTR的有效性和安全性对于临床实践至关重要.

研究的目的:

系统地审查和元分析器件辅助EFTR在结肠和直肠中的成功和安全性.
评估与EFTR相关的临床和技术成功率,手术持续时间和不良事件.

主要方法:

在Embase,PubMed和Medline数据库中进行了全面的文献搜索,截至2022年10月.
包括的研究重点是针对结直肠病变的设备辅助EFTR.
主要结局是R0切除 (临床成功);次要结局包括技术成功和不良事件.

主要成果:

分析包括29项研究,包括3467名患者和3492个病变.
在87.1%的手术中取得了技术上的成功,R0切除率为81.8%.
总体不良事件发生率为11.9%,主要不良事件需要手术发生在2.5%的病例中.

结论:

设备辅助的EFTR证明了对腺瘤和亚皮质结直肠病变的安全性和有效性是有利的.
需要进一步的比较研究来评估EFTR与传统的切除技术 (如内镜粘膜切除和粘膜下剖析) 相比.

关键词:

对于EFTR来说,这是一个很好的方法.进行内镜检查.完全厚度切除的切除方法这是一个元分析.

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