罗班斯2:对干预的非随机研究的一种修订过的偏差风险评估工具
Hyun-Ju Seo1, Soo Young Kim2, Yoon Jae Lee3
1College of Nursing, Chungnam National University, Daejeon, Korea.
Korean journal of family medicine
|July 9, 2023
概括
对非随机化研究的修订后的偏差风险评估工具 (RoBANS 2) 为干预研究提供了改进的偏差评估. 它证明了相当可靠和有效性,增强了对非随机研究的系统审查.
科学领域:
- 系统审查方法论 系统审查方法论
- 基于证据的医学基于证据的医学.
- 健康研究方法 卫生研究方法
背景情况:
- 偏差风险评估对于随机和非随机研究的系统审查至关重要.
- 自2013年以来,非随机化研究的初始偏差风险评估工具 (RoBANS) 已被广泛采用.
- 现有的工具和用户反突出了非随机研究偏差评估的改进领域.
研究的目的:
- 对RoBANS工具进行修订和改进,以便在对干预的非随机研究中进行更强大的偏差风险评估.
- 纳入非随机研究设计的具体考虑,包括选择和检测偏差.
- 在评估框架内提高结果测量的可靠性和有效性.
主要方法:
- 专家对现有工具的审查和对用户调查的分析.
- 修改RoBANS以包括与非随机干预研究相关的额外偏差领域.
- 对修订后的工具 (RoBANS 2) 的心理测量评估,以评估可靠性和有效性.
主要成果:
- 罗班斯2包括增强的选择和检测偏差领域和详细的参与者可比性.
- 心理测量评估显示可接受的评价者间可靠性 (加权卡帕:0.250.49) 和构造有效性.
- 在具有高或不清楚偏差的研究中,发现干预效应被高估了,这支持了RoBANS 2的构造有效性.
结论:
- 修订后的RoBANS 2工具证明了可接受的可行性,相当到中等的可靠性和构造有效性.
- 罗班斯2提供了一个全面的框架,用于评估干预的非随机研究中的偏差风险.
- 这种增强的工具支持在系统审查中更准确地解释来自非随机研究的证据.
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