使用生物反应器生产聚甲酸的有机废物的利用:最近的进展,可持续的方法,挑战和未来的前景
Lalit Goswami1, Anamika Kushwaha1, Suchada Chanprateep Napathorn2
1Department of Chemical Engineering, Chungbuk National University, Cheongju, Chungbuk 28644, Republic of Korea.
International journal of biological macromolecules
|July 9, 2023
概括
微生物聚酸酸盐 (PHA) 提供了对塑料污染的可生物降解解决方案. 本次审查强调使用废物流作为可持续PHA生产的低成本原料,旨在实现循环生物经济.
科学领域:
- 生物技术和工业微生物学
- 聚合物科学 聚合物科学
- 环境科学 环境科学
背景情况:
- 微生物聚酸酸盐 (PHA) 是可生物降解的聚合物,有可能减轻石油衍生的塑料污染.
- 挑战包括不断升级的废物管理问题和与PHA生物合成纯原料相关的高成本.
- 迫切需要将工业废物流利用为PHA生产的可持续原料.
研究的目的:
- 审查目前利用低成本碳基质用于微生物PHA生产的进展情况.
- 探索有效的上游和下游流程,以及废物流回收以实现流程循环.
- 讨论提高PHA生产率和降低商业化成本的策略.
主要方法:
- 对使用废物流进行微生物PHA生物合成的最新文献的审查.
- 对PHA生产的各种生物反应器系统 (批量,料批量,连续,半连续) 的分析.
- 检查生命周期和技术经济分析,代谢工程,合成生物学和自动化策略.
主要成果:
- 成功地利用各种工业废物流作为PHA生产的成本有效的原料.
- 通过优化上游/下游流程和生物反应器系统,证明了PHA生产率的提高和成本的降低.
- 确定影响PHA商业化的关键因素以及扩大PHA多样性的策略.
结论:
- 价值化PHA生产的废物流对于可持续和循环生物经济至关重要.
- 涉及原料选择,工艺优化和先进生物技术的综合方法可以显著降低PHA成本.
- 未来的新陈代谢工程和自动化等战略是实现"零废"目标和广泛商业化PHA的关键.
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