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来自骨髓介质干细胞的外体穿MYCBPAP调节了突触重塑,并改善了大鼠的缺血性中风

Qiuyue Yan1, Yong Yin1, Xuechun Li1

  • 1Department of Neurology, Cangzhou Central Hospital, Cangzhou 061001 Hebei, PR China.

Journal of chemical neuroanatomy
|July 9, 2023
PubMed
概括

骨髓衍生外体 (BMSC-exo) 在中风模型中促进神经恢复. 这些外体携带MYCBPAP蛋白质,促进突触重塑,为缺血性中风提供潜在的治疗策略.

关键词:
骨髓衍生中酶体干细胞是骨髓衍生中酶体干细胞.异构体是什么? 异构体是什么? 外构体是什么?这就是MYCBPAP.自发高血压的老鼠.突触重塑 突触重塑的重塑

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An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
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