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Updated: Jul 24, 2025

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
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Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

Published on: April 27, 2017

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高稳定性和选择性阿德伦美杜林类似物的合理设计

Eva-Maria Jülke1, Jan-Patrick Fischer1, Sylvia Els-Heindl1

  • 1Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany.

Journal of peptide science : an official publication of the European Peptide Society
|July 9, 2023
PubMed
概括

研究人员开发了一种具有长期血管扩张作用的稳定阿德伦美杜林 (ADM) 模拟剂. 这种新保持了对上腺素1受体 (AM1R) 的高活性和选择性,克服了原始激素的局限性.

关键词:
在GPCR中,GPCR是指GPCR.的稳定性 的稳定性酸合成的合成选择性的选择性

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