对于与家族腺瘤多重异位症相关的十二指甲腺多重异位症的强化内镜切除策略
Kentaro Iwata1,2, Motohiko Kato1, Motoki Sasaki1
1Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan.
Journal of gastroenterology and hepatology
|July 9, 2023
概括
密集的内镜切除有效地减少了家族腺瘤多样性 (FAP) 患者的十二指腺多样性,降低了癌症风险. 这种方法降低了病变的阶段,在大多数情况下避免了手术.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 遗传学 是一个遗传学.
背景情况:
- 亲属腺多重症 (FAP) 患者由于多重十二指甲状腺多重症,因此患十二指甲癌的风险很高.
- 强化内镜切除是一种综合策略,结合了各种内镜治疗.
研究的目的:
- 评估FAP患者十二指腺多重症的密集内镜切除的可行性和有效性.
- 评估这种策略对病变降级和需要手术的影响.
主要方法:
- 对28名FAP患者进行了回顾性观察性研究,这些患者患有多重十二指甲状腺多重症,经历了重复的内镜切除.
- 使用各种内镜技术,包括冷多角切除术,EMR,UEMR,ESD和内镜乳头切除术.
- 在治疗前和治疗后评估斯皮格尔曼指数 (SI) 和斯皮格尔曼阶段 (SS).
主要成果:
- 在138次治疗中移除了1040个病变;平均随访时间为3.2年.
- 强化治疗降低了中位数SI,并显著降低了斯皮格尔曼第四阶段的比例,从61%降至13%.
- 在随访期间,没有患者需要进行手术双管切除术.
结论:
- 密集的内镜切除是一种可行的和有效的策略,用于管理FAP中的十二指甲状腺多重症.
- 这种方法有可能降低十二指肠病变的发展阶段,防止需要手术.
相关概念视频
Inflammatory Bowel Disease V: Surgical Management
171
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
171
Endoscopic Procedures V: ERCP
424
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
Patient...
424


