相关实验视频
Updated: Jul 24, 2025

06:11
A Conflict Model of Reward-seeking Behavior in Male Rats
Published on: February 20, 2019
7.5K
药物治疗和博障碍:一个叙事审查
Rezkalla Farkouh1, Sophie Audette-Chapdelaine2, Magaly Brodeur2
1Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada.
Journal of addictive diseases
|July 9, 2023
概括
对博障碍 (GD) 的药物治疗显示出混合的结果,一些药物显示出小到中度的影响. 需要更严格的试验来确认这种成障碍的疗效和指导治疗.
科学领域:
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
- 成 药物 药物 药物 药物
背景情况:
- 博障碍 (GD) 是一种具有重大健康和社会经济后果的重大精神疾病.
- 它的慢性和复发性需要有效的治疗策略来改善患者的功能.
研究的目的:
- 进行叙事审查,评估药物治疗博障碍的有效性和安全性.
- 总结有关GD药理干预的当前证据.
主要方法:
- 在主要数据库 (Medline,Embase,Cochrane Central) 进行全面的文献搜索,以进行系统性审查,元分析和评论.
- 包括2019年以来从包括Prospero和Clinicaltrials.gov.gov在内的数据库中发布的临床试验.
主要成果:
- 鉴定了八种药理学药物 (纳尔特雷,纳尔梅芬,帕洛克塞丁,弗卢沃胺,西塔洛普拉姆,埃斯卡托普拉姆,,托皮拉玛酸).
- 一些研究表明,在减少GD症状方面,效果大小小到中等,特别是在某些药物和后期分析中.
结论:
- 目前,GD中药物治疗的证据是相互矛盾的和不确定的.
- 药物治疗可能是有前途的,特别是当它适用于并发性精神疾病时.
- 未来严格的试验对于克服研究设计的局限性和建立最终的疗效数据至关重要.
相关概念视频
Drug Abuse and Addiction: Pharmacological Phenomena
552
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
552
Drug Therapy
74
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
74
Psychosis: Goals of Pharmacotherapy
170
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
170
Drug Dependence
1.1K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.1K
Diagnostic and Statistical Manual of Mental Disorders (DSM)
99
The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
99
CNS Depressants: Alcohol and Nicotine
274
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
274

