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Updated: Jul 24, 2025

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
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一个aptamer功能化的DNA电路,以建立T细胞和癌细胞之间的人工相互作用

Zhimin Wang1, Yue Zhang1, Limei Wu1

  • 1Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha, Hunan 410082, China.

Angewandte Chemie (International ed. in English)
|July 9, 2023
PubMed
概括

研究人员开发了一种DNA电路,以增强T细胞免疫疗法. 这种由胺酶功能化的电路增强了T细胞对抗癌细胞的活性,为癌症治疗提供了一种新的非遗传战略.

关键词:
亚博体育官网 亚博体育官网 亚博体育官网 亚博体育官网 亚博体育官网细胞与细胞的相互作用这就是DNA电路.接收器 接收器 接收器在T细胞免疫力方面.

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