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记忆障碍老年人的24小时休息/活动节奏:与认知表现和抑郁症状相关联

Inga M Antonsdottir^1,2, Dominique V Low³, Diefei Chen^4,5

¹Johns Hopkins School of Nursing, 525 N. Wolfe Street, Baltimore, MD, 21205, USA.

Advanced biology

|July 9, 2023

概括

患有记忆障碍的老年人的循环节律变化与情绪和认知功能有关. 特定的休息/活动模式与抑郁症状,记忆回忆和整体认知相关.

科学领域:

老年学是一门学科.
神经科学是一个神经科学.
睡眠医学睡眠医学

背景情况:

循环节律的改变在老年人中很常见,特别是那些有记忆障碍的人.
在这个人群中,休息/活动节奏 (RAR) 与神经精神症状 (包括抑郁症) 和认知功能之间的关系尚不清楚.

研究的目的:

为了调查行为摄影测量RAR与抑郁症状,全球认知表现和老年人有记忆障碍的延迟单词回忆之间的关联.

主要方法:

使用函数对标尺回归 (FOSR) 来分析44名老年人患有记忆障碍的数据.
收集了大约6天的休息/活动模式的动作图数据.
使用贝克抑郁症目录-II (BDI-II) 评估抑郁症状,使用迷你精神状态检查 (MMSE) 评估全球认知,并通过建立阿尔茨海默病注册表联盟 (CERAD) 推迟召回.

主要成果:

较高的抑郁症状 (BDI-II) 与在特定的白天,晚上和夜间期间的活动增加有关.
更好的延迟单词回忆 (CERAD) 与晚上晚些时候更大的活动有关.
较高的全球认知表现 (MMSE) 与早上和下午活动增加有关.

结论:

休息/活动节律的特定时间变化与老年人患有记忆障碍的情绪和认知表现有关.
这些发现表明,昼夜节律障碍可能在这种人口群体中发挥神经精神症状和认知衰退的表现作用.

关键词:

动画摄影 (actigraphy) 是一种摄影方式.昼夜节律昼夜节律痴呆症痴呆症是一种痴呆症.抑郁抑郁症抑郁症抑郁症是一种记忆记忆记忆记忆记忆

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