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2型糖尿病的计算机化指甲折叠视频毛囊镜:对102名门诊患者的横截面研究

Giuseppe Lisco¹, Vincenzo Triggiani¹

¹Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari Aldo Moro, Bari, Italy.

Journal of diabetes

|July 9, 2023

概括

2型糖尿病 (T2D) 与指甲微血管变化有关,特别是在血糖控制不良的情况下. 计算机化指甲视频毛囊镜 (CNVC) 揭示了这些变化,有助于评估并发症.

科学领域:

血管生物学血管生物学
内分泌学在内分泌学.
医疗成像医学成像

背景情况:

2型糖尿病 (T2D) 显著影响血管健康,需要对慢性并发症,特别是微循环进行彻底评估.
计算机化指甲视频毛囊镜 (CNVC) 是检查指甲微血管的准确方法,其在T2D患者中的实用性正在积极探索.

研究的目的:

在T2D患者中表征指甲微血管.
为了将微血管发现与血糖控制水平 (HbA1c) 相关联.
将微血管变化与慢性微血管和宏血管并发症的存在联系起来.

主要方法:

一项涉及102名T2D门诊患者的横截面研究,使用计算机化指甲折叠视频毛细管显微镜 (CNVC) 使用300倍放大.
使用标准化参数来描述毛细血管的外观和毛细血管的变化.
通过IIEF-5评估的患有慢性并发症 (包括勃起功能障碍 (ED)) 和没有慢性并发症 (包括勃起功能障碍 (ED)) 的患者之间的毛细管学参数比较 (HbA1c ≥7%) 与更好 (HbA1c <7%) 的葡萄糖控制.

主要成果:

与HbA1c<7%的患者相比,HbA1c≥7%的患者表现出更厚和更长的指甲毛细血管,而HbA1c<7%的患者则表现出更厚和更长的指甲毛细血管.
在患有HbA1c≥7%的患者中,观察到更高频率的阳和微动脉瘤.
微动脉瘤在患有动脉狭窄症的患者中更为普遍,而患有ED的患者表现出更少的奇怪形状毛细血管.

结论:

在T2D患者中存在显著的指甲折微血管变化.
这些变化经常与血糖控制不良,勃起功能障碍和动脉狭窄症有关.
需要进一步的研究来确定CNVC在预测T2D并发症和监测微循环治疗疗效方面的作用.

关键词:

二型糖尿病是第二种糖尿病.心血管疾病心血管疾病慢性脏疾病慢性脏疾病计算机化的指甲折叠视频毛细毛囊显微镜.糖尿病视网膜病变糖尿病视网膜病变这是勃起功能障碍.2 型糖尿病 2 型糖尿病勃起功能障碍是一种障碍.心血管疾病心血管疾病慢性病是一种慢性病.糖尿病视网膜病变计算机化甲视频毛细血管镜头

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