分离到多的微观结肠炎的临床影响
Caroline Miller1, Christa Whitney-Miller1, Mark G Ettel1
1Department of Pathology, University of Rochester Medical Center, Rochester, NY, USA.
International journal of surgical pathology
|July 10, 2023
概括
偶尔在多体中发现的多型微观结肠炎可能会导致某些患者的慢性腹或微观结肠炎. 病理学家应将其与传统的显微性结肠炎区分开来,以便进行适当的临床后续检查.
科学领域:
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
背景情况:
- 显微性结肠炎 (MC) 通常通过随机结肠活检诊断慢性腹.
- 很少情况下,多体可以表现出MC的组织学特征,称为多体微观结肠炎 (PMC).
研究的目的:
- 为了将PMC患者与常规息肉的对照患者进行比较.
- 确定与PMC相关的临床影响和结果.
主要方法:
- 追溯搜索PMC患者的医疗记录.
- 选择具有常规聚体的对照患者.
- 对两个组的组织学,内镜和临床数据的审查.
主要成果:
- 确定了26例PMC病例;69%是淋巴细胞大肠炎,31%是原性大肠炎.
- 患者的PMC年龄大于对照组 (平均年龄为60岁与66岁).
- 随访显示,33%的PMC患者患有慢性腹,而对照组为12%;13%患有MC,而对照组为0%.
结论:
- PMC可以发生在无症状的个体中,并且通常不会导致慢性腹.
- 然而,在随访时,一小部分PMC患者可能会出现慢性腹或常规MC.
- 将PMC与传统MC区分开来,对于指导临床管理和后续决策至关重要.
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