瘦非酒精性脂肪性肝病和肉类症
Milian Chen1, Ying Cao1, Guang Ji1
1Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Frontiers in endocrinology
|July 10, 2023
概括
瘦非酒精性脂肪性肝病 (NAFLD) 与肌肉损失状况的萨尔科佩尼亚有关. 本综述探讨了它们之间的联系,并提出了减轻瘦肉性NAFLD和肉类的风险的策略.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 代谢疾病 代谢疾病
- 老年学是一门学科.
背景情况:
- 非酒精性脂肪性肝病 (NAFLD) 是一种普遍存在的全球性肝病.
- 在非肥胖个体中发生的瘦身NAFLD越来越被认可.
- 瘦身NAFLD经常伴随着肉症,其特征是肌肉损失.
研究的目的:
- 审查萨尔科佩尼亚和瘦肉性NAFLD之间的关联.
- 阐明这些疾病之间联系的病理机制.
- 提出降低风险的策略.
主要方法:
- 文献综述和现有研究的综合.
- 分析涉及代谢炎症和胰岛素抵抗的病理途径.
- 讨论临床影响和治疗方法.
主要成果:
- 瘦肉性NAFLD的病理特征,包括内脏肥胖和代谢性炎症,有助于萨尔科佩尼亚.
- 肌肉损失加剧了子宫外脂肪积累,恶化了瘦肉性NAFLD.
- 瘦肉性NAFLD和肉毒之间存在双向关系.
结论:
- 麻症和瘦肉性NAFLD有共同的病理生理机制.
- 针对代谢健康和肌肉保存的干预措施可能对这两种情况都有好处.
- 需要进一步的研究来制定有效的管理策略.
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