美国男性中中性粒细胞与淋巴细胞比率和勃起功能障碍之间的关联:基于人口的横截面研究
Xingliang Feng1,2, Yangyang Mei3, Xiaogang Wang1,2
1Department of Urology, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Frontiers in endocrinology
|July 10, 2023
概括
较高的中性粒细胞与淋巴细胞比率 (NLR) 与成年男性的勃起功能障碍 (ED) 有关. 这种炎症标志物与美国成年人ED患病率有显著的关联.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 炎症标志物的炎症标志物
- 公共卫生 公共卫生
背景情况:
- 勃起功能障碍 (ED) 是一种常见的疾病,影响了许多成年男性.
- 炎症在各种健康状况中起作用,中性粒细胞与淋巴细胞的比率 (NLR) 是一个易于获得的标志物.
研究的目的:
- 研究美国成年男性中中性粒细胞与淋巴细胞比率 (NLR) 和勃起功能障碍 (ED) 之间的关联.
- 通过使用大型国家健康数据库,分析NLR作为ED的潜在指标.
主要方法:
- 利用了2001-2004年国家健康和营养检查调查 (NHANES) 的数据.
- 对3012名参与者进行了统计分析,以检查NLR和ED患病率之间的关系.
- 调整以混变量来评估独立协会.
主要成果:
- 总共有3012名参与者被纳入,其中18.9%的人经历ED.
- 与没有ED的参与者相比,ED的参与者中的NLR水平显著更高.
- 在NLR和ED之间观察到U形关系,在NLR1.52.以上观察到更强的相关性.
结论:
- 在美国成年人中,高NLR和ED的发生之间存在统计学上显著的关联.
- NLR是一种与ED相关的简单,廉价和可访问的炎症参数.
- 需要进一步的研究来验证这些发现,并探索潜在的机制.
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