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与破坏性手术出血相关的临床和经济负担:回顾性数据库分析

Stephen S Johnston¹, Mosadoluwa Afolabi¹, Pranjal Tewari²

¹MedTech Epidemiology and Real-World Data Sciences, Johnson and Johnson, New Brunswick, NJ, USA.

ClinicoEconomics and outcomes research : CEOR

|July 10, 2023

概括

在手术期间的破坏性出血显著增加了重症监护室的停留时间,住院时间和费用,即使使用了静血剂. 这凸显了对手术患者更好的出血控制方法的需求.

科学领域:

手术结果研究研究.
卫生经济学卫生经济学
患者安全患者安全

背景情况:

静血剂对于治疗手术出血至关重要.
尽管使用血静止剂,但仍可能出现破坏性出血,影响患者的治疗结果.
了解破坏性出血的后果对于改善手术护理至关重要.

研究的目的:

为了比较手术期间有和没有破坏性出血的患者的临床和经济结果.
评估破坏性出血对重症监护室 (ICU) 住院,呼吸机使用和住院时间 (LOS) 的影响.
评估破坏性出血与医院费用和再入院率的关联.

主要方法:

总理医疗保健数据库 (2019-2019) 的回顾性分析.
包括51,448名成年患者,他们接受了9种特殊的手术程序之一,使用止血剂.
使用多变量分析,比较患有和没有破坏性出血的患者之间的结果.

主要成果:

16%的患者经历了破坏性出血.
在大多数手术中,扰乱性出血显著增加了ICU入院风险,呼吸机使用,ICU日数和LOS.
破坏性出血患者的总医院费用明显高于破坏性出血患者.
住院死亡率和90天再入院率也有所上升.

结论:

破坏性出血在各种手术环境中造成了重大的临床和经济负担.
这些发现强调了改善干预措施的必要性,以有效地管理手术出血.
进一步研究先进的静血技术是有必要的,以减轻这些不良结果.

关键词:

在这里,RWE RWE RWE 流血的负担流血的负担卫生资源利用率卫生资源利用率血静剂是一种血静剂.医院费用医院费用医院费用现实世界的证据.

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