与COVID-19的严重程度相关的风险因素
Martono1, Fitri Fatmawati1, Sri Mulyanti1
1Department of Nursing, Politeknik Kesehatan Kemenkes Surakarta, Surakarta, Indonesia.
The Malaysian journal of medical sciences : MJMS
|July 10, 2023
概括
了解COVID-19严重性风险因素至关重要. 关键因素包括年龄,并发症,吸烟和未接种疫苗,这突显了针对性干预的必要性.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 新型冠状病毒疾病 (COVID-19) 引发了全球卫生危机,病毒变异的演变加剧了这种疾病的传播能力和毒性.
- 识别COVID-19易感性和严重性的风险因素对于有效的疾病控制策略至关重要.
- 以前的研究已经探索了COVID-19结果的各种决定因素,需要进行综合审查.
研究的目的:
- 系统地审查和综合现有关于COVID-19严重程度相关的风险因素的文献.
- 确定预测严重COVID-19结果的关键人口,临床和行为因素.
- 提供基于证据的摘要,以告知公共卫生干预和临床管理.
主要方法:
- 使用主要科学数据库 (谷歌学者,PubMed,ProQuest,ScientDirect) 对2020年至2021年间发表的研究进行了全面的文献审查.
- 系统审查和元分析 (PRISMA) 的首选报告项目战略被采用,以确保根据预定义的纳入标准进行严格的文章选择.
- 九项符合纳入标准的研究被评估为质量,数据提取和合成,以确定一致的风险因素.
主要成果:
- 几种风险因素一直被确定为导致COVID-19严重性的因素,包括晚年,男性性别和慢性并发症的存在.
- 与严重的COVID-19明显相关的特定并发症包括心血管疾病,糖尿病,高血压,功能衰竭和癌症.
- 吸烟史,尤其是未接种疫苗,被确定为COVID-19严重程度增加的显著风险因素.
结论:
- 个体特征,如年龄和性别,再加上先前存在的慢性疾病和吸烟史,显著提高严重COVID-19的风险.
- 疫苗接种状况成为关键决定因素,未接种疫苗的人面临严重疾病进展的风险要大得多.
- 这些发现强调了通过公共卫生倡议,疫苗接种运动和量身定制的临床管理来解决这些风险因素的重要性,以减轻COVID-19的影响.
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