大型抑郁症与甲状腺功能障碍相关联:系统性审查
Anjali Desai1, Anjana Bajgain1, Asna Ali1
1Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Cureus
|July 10, 2023
概括
大型抑郁症 (MDD) 与高甲状腺水平有关. 治疗甲状腺功能障碍症和高水平可能会减少患者的抑郁症状,改善心理健康.
科学领域:
- 内分泌学 在内分泌学.
- 神经精神病学是一种神经精神病学.
- 心理健康 心理健康
背景情况:
- 重度抑郁症 (MDD) 是一种普遍存在的神经精神疾病,其原因有多种因素.
- 甲状腺功能障碍症是一种内分泌疾病,通常与精神病有关,而不是抑郁症.
- 甲状腺水平升高与抑郁症状之间的联系需要进一步研究.
研究的目的:
- 系统地审查主要抑郁症和血清副甲状腺水平升高之间的相关性.
- 探索甲状腺功能障碍症对心理健康和抑郁症状的影响.
- 为了指导临床医生在评估和管理过多甲状腺症患者的抑郁症.
主要方法:
- 在五个数据库 (MEDLINE,PubMed,PMC,ScienceDirect,Google Scholar) 进行系统的文献搜索.
- 使用的关键词:MDD,抑郁症和副甲状腺功能障碍.
- 包括过去10年的混合方法研究 (观察性,RCT,病例报告,综述),重点是成年人 (>18岁).
主要成果:
- 包含11篇文章 (7篇观察报告,4篇案例报告) 进行了定性综合.
- 在高副甲状腺水平,高,高性酸酶,低和增加抑郁症状之间发现了联系.
- 治疗高血症或副甲状腺切除术导致抑郁症状的减少.
结论:
- 大型抑郁症和副甲状腺功能障碍之间存在显著的关联.
- 临床医生应评估患有副甲状腺水平升高的患者是否有抑郁症状.
- 需要进一步的随机对照试验来证实在甲状腺功能障碍症中治疗抑郁症的疗效.
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