SR-TWAS:利用多个参考面板来提高TWAS的性能,通过整合机器学习来提高TWAS的性能

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Updated: Jul 24, 2025

Integrating Remote Sensing with Species Distribution Models; Mapping Tamarisk Invasions Using the Software for Assisted Habitat Modeling SAHM
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Published on: October 11, 2016

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Randy L Parrish, Aron S Buchman, Shinya Tasaki

    medRxiv : the preprint server for health sciences
    |July 10, 2023
    PubMed
    概括

    基于堆叠回归的TWAS (SR-TWAS) 通过优化组合多个基因表达赋值模型来增强复杂疾病的基因发现. 这种方法增加了统计能力,识别了阿尔茨海默氏症和帕金森病的新风险基因.

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