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Updated: Jul 24, 2025

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A High-throughput, High-content, Liquid-based C. elegans Pathosystem
Published on: July 1, 2018
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发现使用生物有机金属化学对真核病原体的新型广谱抗感染药物的发现
bioRxiv : the preprint server for biology
|July 10, 2023
概括
新的可纳衍生物对真菌感染和寄生虫有广泛的活性. 这些具有成本效益的化合物为被忽视的热带疾病和新出现的感染提供了潜在的新疗法.
科学领域:
- 药用化学 医学化学
- 药物发现 药物发现 药物发现
- 寄生虫学的寄生虫学
背景情况:
- 耐药性需要新的广泛抗感染剂,特别是对于被忽视的热带疾病 (NTDs).
- 开发负担得起和可访问的治疗方法对于受NTD影响的弱势群体至关重要.
结论:
- 简单地修改可纳可以产生具有抗真菌和寄生虫感染潜力的广谱药物.
- 新衍生品为开发对NTD和其他新兴传染病的经济有效治疗提供了有希望的途径.
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