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Updated: Jul 24, 2025

Production of a SARS-CoV-2 Virus-Like-Particle System to Investigate Viral Life Cycles In Vitro
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Production of a SARS-CoV-2 Virus-Like-Particle System to Investigate Viral Life Cycles In Vitro

Published on: June 6, 2025

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主体G3BP与病毒核体蛋白之间的相互作用调节了SARS-CoV-2的复制

Zemin Yang1, Bryan A Johnson2, Victoria A Meliopoulos3

  • 1Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.

bioRxiv : the preprint server for biology
|July 10, 2023
PubMed
概括

SARS-CoV-2 N蛋白与G3BP1之间的相互作用抑制了压力颗粒的形成,促进了病毒复制. 破坏这种相互作用可以显著降低病毒载量和疾病严重程度.

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