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Updated: Jul 24, 2025

Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library
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Published on: April 6, 2012

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目标导向的microRNA降解调节了哺乳动物的发育性microRNA表达和胚胎生长

Benjamin T Jones1, Jaeil Han1, He Zhang2

  • 1Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

bioRxiv : the preprint server for biology
|July 10, 2023
PubMed
概括

目标导向的miRNA降解 (TDMD) 控制了微RNA (miRNA) 的水平. 失去了关键的TDMD因子Zswim8,导致发育缺陷,并揭示了影响哺乳动物体型的广泛miRNA调节.

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