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Updated: Jul 24, 2025

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
10:10

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

Published on: March 31, 2019

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霍克斯德RNA激活癌症转录程序和全基因组超强增强器

Evgeny Deforzh1, Prakash Kharel2, Anton Karelin1

  • 1Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

bioRxiv : the preprint server for biology
|July 10, 2023
PubMed
概括

一种新的长非编码RNA,HOXDeRNA,通过取代基因抑制和激活瘤基因来驱动质母细胞瘤. 这种RNA四重复结构是它在脑瘤形成中的关键作用.

关键词:
在 PRC2 中,PRC2 是 PRC2 的第一个类型.星球细胞是星球细胞.大脑瘤 大脑瘤增强RNA的RNA增强剂可以增强RNA.质瘤 质瘤 是一种长非编码RNA是什么意思rG4 4 的时间.干细胞是干细胞的组成部分.这些超级增强剂是超级增强剂.转录因子是一种转录因子.

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