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在患有CARD9缺乏症的患者中,对深层皮肤植物病进行手术治疗

Maha El Maati¹, Zakia Berjaou², Zaineb Hammouch³

¹Dematology Department, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco.

Journal of surgical case reports

|July 10, 2023

概括

在一个患有CARD9缺乏症的患者中,呈现了一种罕见的Trichophyton Rubrum引起的深层皮肤植物病例. 这种遗传状况,即CARD9缺乏症,使个体易患严重的真菌感染,突出显示了遗传因素在复发性皮肤植物病中的重要性.

科学领域:

菌类学菌类学是指菌类学.
遗传学遗传学是一个
皮肤病学皮肤病学

背景情况:

深层皮肤植物病是一种严重的皮肤真菌感染,由皮肤植物引起.
CARD9 缺陷是深层皮肤植物病的遗传风险因素,在地中海地区尤其明显.
这种情况可以表现为各种形式,包括马约基粒瘤和皮下.

研究的目的:

报告一个独特的深层皮肤植物病例,在一个患有CARD9缺乏症的患者中广泛参与.
突出这一罕见疾病的临床表现,诊断发现和成功管理.
强调CARD9突变在对深层真菌感染的易感性中的作用.

主要方法:

一个23岁的男性患有痕性脱发症和皮下的临床病例介绍.
菌根学分析以确定致病原体,Trichophyton Rubrum. 这种菌株是最常见的.
分子研究以检测CARD9突变并评估感染程度 (鼻和淋巴结).

主要成果:

这位患者出现了痕性脱发,皮下,以及虫感染.
菌根分析证实Trichophyton Rubrum是深层皮肤植物病的原因.
分子分析发现了CARD9突变,表明了遗传倾向,并揭示了鼻和淋巴结的参与.

结论:

深层皮肤植物病可以表现为异常和严重的表现,如皮下和广泛感染.
卡德9缺乏是深层皮肤植物病的重要危险因素,需要对易受感染的个体进行遗传研究.
成功管理涉及手术干预 (液排水) 和抗真菌药物治疗的组合.

关键词:

在CARD9中发生突变.深层皮肤植物病深层皮肤植物病.菌根腹菌类腹创伤性脱毛症 (alopecia) 是一种脱毛症.外科手术排水的使用.

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