家庭性松性曲:一个病例报告和文献综述
Kasama Tejapira1, Poonkiat Suchonwanit1
1Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Clinical, cosmetic and investigational dermatology
|July 10, 2023
概括
家庭性皮质障碍性 (FDC) 是一种罕见的遗传性皮肤疾病,导致广泛的,无症状的皮质障碍性斑块. 本报告详细介绍了一个病例,治疗反应,并介绍了这种具有挑战性的疾病的皮肤镜检测结果.
科学领域:
- 皮肤病学 皮肤病学
- 遗传学 遗传学 是一个
- 组织病理学 组织病理学
背景情况:
- 家庭性皮质障碍性共 (FDC) 是一种自体主导的遗传性皮肤疾病.
- 它的特征是一般化的多个离散的形状的形状的形状的形状.
- 组织病理学显示出异性表皮或卵泡状结构的异性皮质.
研究的目的:
- 报告一个54岁女性的FDC病例.
- 描述临床表现,组织病理学发现和治疗反应.
- 记录FDC的第一个皮肤镜检测结果,并审查现有的文献.
主要方法:
- 诊断的临床检查和组织病理学评估.
- 使用局部视网类药物和尿素奶油进行治疗.
- 对21个FDC病例进行皮肤镜评估和文献综述.
主要成果:
- 一个54岁的女性呈现了20年历史的泛性皮病.
- 诊断证实了临床和组织病理学发现.
- 在3个月的局部治疗后观察到轻微改善.
结论:
- FDC是一种良性但耐治疗的遗传性皮肤疾病.
- 局部的视网类药物和尿素奶油可能会略有改善.
- 皮肤镜检测结果首次被描述,有助于诊断.
相关概念视频
Cohesins
Cohesin protein complexes are a molecular glue that holds two sister chromatids together. They play an important role both in mitosis and meiosis. In mitosis, all cohesin complexes present on the chromosomes are removed before the start of the anaphase stage.
Cohesin complexes in Meiotic Division
Meiosis involves two distinct rounds of chromosomal segregation and cell divisions— Meiosis I followed by Meiosis II – producing four daughter cells. Meiosis I includes the separation of homologous...
Cohesin complexes in Meiotic Division
Meiosis involves two distinct rounds of chromosomal segregation and cell divisions— Meiosis I followed by Meiosis II – producing four daughter cells. Meiosis I includes the separation of homologous...
Accessory Structures of the Skin: Sebaceous Glands
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
COPD: Pathogenesis and Clinical Features
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Cystic Fibrosis: Pathogenesis
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...
Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...


