关于红细胞输血在非心脏胸部手术中的最新情况
Christian Galata1, Eric Dominic Roessner1, Frank Dette2
1Department of Thoracic Surgery, Center for Thoracic Diseases, University Medical Center Mainz, Johannes Gutenberg University Mainz, Mainz, Germany.
在非心脏胸部手术中,红细胞 (RBC) 输血率较低,特别是在选择性肺切除中. 然而,紧急病例,开放式手术和血症显著增加了输血风险,突出显示了需要量身定制的血液管理策略.
科学领域:
- 胸部外科手术 胸部外科手术
- 麻醉学 麻醉学
- 输血医学 输血医学
背景情况:
- 非心脏胸部手术涉及影响胸腔的手术,不包括心脏.
- 红细胞 (RBC) 输血对于管理外科手术期间的血液损失至关重要.
- 识别红细胞输血的风险因素对于优化患者的治疗结果至关重要.
研究的目的:
- 在接受非心脏胸部手术的患者中,识别和评估与红细胞输血相关的关键风险因素.
- 分析患者人口统计学,手术特征和术后红细胞输血的需要之间的关联.
主要方法:
- 追溯分析了2021年1月至12月期间接受非心脏胸部手术的379名患者的数据.
- 收集的数据包括血液请求和外科手术期间红细胞输血事件.
- 用多变量分析来确定输血的独立风险因素.
主要成果:
- 整体红细胞输血率为7.4%,非选择性 (20.2%) 与选择性 (2.5%) 病例的比率明显高.
- 肺 (44.7%),开放性手术,手术前低血红蛋白 (<10.4 g/dL),以及年龄较大被确定为红细胞输血的独立风险因素.
- 手术前的血红蛋白水平是输血的最强预测因素,切断值为<10.4g/dL.
结论:
- 在非心脏胸部手术中,红细胞输血率通常很低,特别是在选择性肺切除时.
- 在紧急病例,开放性手术,特别是患有 empyema 的患者中,高输血率仍然存在.
- 应根据患者特定的风险因素来个性化进行手术前的血液单元请求,以改善输血管理.
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