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相关概念视频

Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

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IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
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Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

10
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
10
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

32
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
32
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

15
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
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Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

26
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
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Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

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Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
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相关实验视频

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Novel and Innovative Hybrid Technique for Type A Aortic Dissection
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周末效应是否存在于急性A型大动脉剖析? - 一个回顾性病例控制研究

Jinlin Wu1, Guang Tong1, Julia Fayanne Chen2

  • 1Department of Cardiac Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.

Journal of thoracic disease
|July 10, 2023
PubMed
概括

周末效应,即周末入院的死亡率上升,似乎不会影响急性A型大动脉剖析 (ATAAD) 的结果. 这项研究发现,在周末和周日治疗的ATAAD患者的死亡率或并发症没有显著差异.

关键词:
一种类型的甲动脉剖析.死亡率 死亡率周末效应是周末的效应.

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科学领域:

  • 心血管外科心血管外科
  • 医学成果研究研究成果
  • 医疗保健服务研究 医疗服务研究

背景情况:

  • 周末效应描述了与周日相比,周末入院或手术的患者的潜在死亡率增加.
  • 急性甲动脉解剖A型 (ATAAD) 是一种危及生命的疾病,需要及时进行手术.

研究的目的:

  • 调查周末效应对急性A型大动脉剖析 (ATAAD) 患者结果的影响.
  • 根据入院日,提供关于ATAAD护理的潜在差异的新证据.

主要方法:

  • 在ATAAD中对周末效应的现有文献进行了全面的元分析.
  • 使用单一中心数据进行了一项回顾性病例控制研究,以分析包括手术死亡率,中风,残肢和连续置换疗法 (CRRT) 在内的主要终点.
  • 倾向分数匹配 (PSM) 用于控制单中心队列中的混变量.

主要成果:

  • 对18462人进行的元分析表明,在周末入院的ATAAD患者的死亡率没有显著增加 (OR:1.16,95%CI:0.94-1.43).
  • 单中心队列 (479名患者) 在周末和周日组之间的主要或次要结果中也没有显著差异,即使在调整了手术前和手术因素后 (调整后OR:0.94,95%CI:0.41-2.02).
  • 在PSM队列中,手术后死亡率 (周末7.2%,周日6.5%) 和整体存活率在两组之间相似 (分别P=1.000和P=0.970).

结论:

  • 周末效应似乎不是影响急性A型大动脉剖析结果的重要因素.
  • 虽然这种特定的情况可能不会受到周末效应的影响,但临床医生应该意识到,这种现象可能是疾病特异性的,并且在不同的医疗保健系统中有所不同.