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肺癌的叶叶切除术后,支气管支气管的危险因素
Junji Ichinose1, Kohei Hashimoto1, Yosuke Matsuura1
1Department of Thoracic Surgical Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan.
Journal of thoracic disease
|July 10, 2023
概括
肺癌分管切除术后的支气管口腔 (BPF) 是一种罕见的并发症. 接受高C反应蛋白右下叶切除术或先前胃外科手术的男性面临BPF风险增加.
科学领域:
- 胸部外科手术 胸部外科手术
- 在瘤学瘤学.
- 肺部医学 肺部医学
背景情况:
- 支气管肺 (BPF) 是为肺癌进行分管切除术后的一种罕见但严重的并发症.
- 识别风险因素对于预防BPF和改善患者结果至关重要.
研究的目的:
- 为了分层风险因素,与发展的支气管支气管 (BPF) 后,为肺癌的脑腔切除术.
主要方法:
- 追溯对3180名患者进行的回顾,这些患者因肺癌而接受了叶片切除 (2005-2020年).
- 分析背景因素,包括并发症,手术前血液检查,呼吸功能,手术细节和淋巴切除术程度.
- 进行了多变量分析,对一小组男性患者进行了多变量分析,这些男性患者接受了右下叶切除术.
主要成果:
- 血压压力的发生率为0.44% (在3,180名患者中14名).
- 在所有接受了右下叶切除术的男性患者中都出现了BPF.
- 显著的危险因素包括年龄较大,大量吸烟,阻塞性呼吸系统衰竭,间歇性肺炎,先前的恶性瘤,先前的胃癌手术和低血清白蛋白.
- 在亚组分析中,高血清C反应蛋白和胃癌手术史与BPF有显著的关联,而支气管茎覆盖率显示出相反的关联.
结论:
- 接受右下叶切除术的男性患者患BPF的风险更高.
- 高血清C反应蛋白和胃癌手术史是BPF的重要危险因素.
- 支气管茎覆盖可能是BPF高风险患者的保护因素.
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