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基于决策树的谷氨基转移酶对高脂血症的影响分析

Tingting Zhang^1,2, Dantong Ouyang^1,2, Chenglin Sun^3,4

¹College of Computer Science and Technology, Jilin University, Changchun, China.

|July 10, 2023

概括

这项研究发现,即使在正常范围内,高马-氨基转移酶 (GGT) 水平也与增加高甘油三血症风险有关. 控制GGT可以帮助减少高脂血症的流行率.

科学领域:

内分泌学在内分泌学.
临床生物化学临床生物化学
公共卫生公共卫生

背景情况:

超脂血是心血管疾病的重要危险因素.
了解肝功能和脂质代谢之间的相互作用对于有效的管理至关重要.
胺转移酶 (GGT) 是肝脏健康和氧化应激的标志物,可能与代谢障碍有关.

研究的目的:

为了研究影响高脂血症的因素.
探索肝功能指标,特别是GGT和高脂血症之间的关系.
确定在门诊环境中与高脂血症相关的一般规则和危险因素.

主要方法:

分析了吉林大学第一医院的7599名门诊患者 (2017-2019) 的数据.
利用多位数回归来确定与高脂血症相关的因素.
采用决策树方法来辨别超脂血症和非超脂血症患者组中的模式.

主要成果:

超脂血症患者在年龄,BMI,SBP,ALT和GGT方面的平均值较高,与非超脂血症患者相比.
多变量分析显示了甘油三水平与SBP,BMI,葡萄糖水平,HbA1c,ALT和GGT之间的关联.
在特定范围内控制GGT (例如,HbA1c<6.0%的<30 IU/L) 显著降低了高甘油三血症的流行率.

结论:

高GGT水平,即使在正常范围内,也与高血糖三血症的患病率增加相关.
在患有正常血糖症和葡萄糖耐受性受损的个体中,控制GGT水平可以减轻超脂血症风险.
GGT 作为高脂血症风险的潜在指标,建议预防治疗目标.

关键词:

谷氨基基转移酶的作用是什么决策树是一个决策树.过高脂血症是什么意思预防预防预防公共卫生公共卫生.

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