骨矿物质密度与老年人心血管疾病之间的关联
1Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Frontiers in public health
|July 10, 2023
概括
较低的股骨矿物质密度与老年人患心血管疾病的风险更高有关. 骨质疏松症显著增加了这种风险,显著的拐点为0.741 gm/cm2.
科学领域:
- 老年学是一门学科.
- 心脏病学 心脏病学
- 骨科 骨科是指骨科的学科.
背景情况:
- 心血管疾病和骨质疏松症在老年人中很普遍.
- 研究越来越多地关注这些疾病之间的病原性联系.
研究的目的:
- 调查老年人骨矿物密度 (BMD) 与心血管疾病 (CVD) 风险之间的关联.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) 的数据.
- 采用多变量逻辑回归,通用添加模型和平滑曲线拟合.
- 应用了两部分线性模型来识别BMD-CVD关系中的拐点.
主要成果:
- Femur BMD 显示出与心血管疾病风险有显著的非线性反向关联,拐点为 0.741 gm/cm2.
- 腰部BMD没有显示出与心血管疾病的显著关联.
- 骨质疏松症与与正常骨质相比,心血管疾病的风险增加了2.05倍.
结论:
- 骨质疏松症与60岁以上成年人心血管疾病的患病率显著相关.
- Femur BMD 表明与心血管疾病风险的负面非线性关系,突出其在心血管健康评估中的重要性.
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