相关实验视频

Updated: Jul 24, 2025

Isolation and Characterization of Dendritic Cells and Macrophages from the Mouse Intestine
09:25

Isolation and Characterization of Dendritic Cells and Macrophages from the Mouse Intestine

Published on: May 21, 2012

39.2K

TSLP/树突细胞轴促进CD4+T细胞对肠道微生物群的耐受性

Jonathan L Messerschmidt, Marjan Azin, Kaitlin E Dempsey

    JCI insight
    |July 10, 2023
    PubMed
    概括

    胸膜层淋巴蛋白 (TSLP) 信号通常通过调节CD4+T细胞扩张和促进Treg分化来预防致命性结肠炎. 这种TSLP-dendritic细胞轴维持肠道对共生微生物的耐受性.

    关键词:
    适应性免疫是一种适应性免疫.细胞因子 (cytokines) 是一种细胞因子.胃肠病学 胃肠病学免疫学 免疫学 免疫学宽容是一种宽容.

    更多相关视频

    Isolation of Murine Lymph Node Stromal Cells05:47

    Isolation of Murine Lymph Node Stromal Cells

    Published on: August 19, 2014

    31.4K
    Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells06:57

    Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells

    Published on: September 18, 2016

    9.1K

    相关概念视频

    Special Features of Adaptive Immunity01:20

    Special Features of Adaptive Immunity

    The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
    The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
    892
    T Cell Types and Functions01:24

    T Cell Types and Functions

    When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
    Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
    1.1K
    T Cell Activation and Clonal Selection01:22

    T Cell Activation and Clonal Selection

    T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
    Naive T cells that have not yet encountered an antigen express two primary CD...
    822
    Cell-mediated Immune Responses01:40

    Cell-mediated Immune Responses

    Overview
    69.0K