心电图异常和心力衰竭的预后不佳,其中保留了喷射分数
Tiantian He1, Chen Liu2, Weihao Liang2
1Department of Obstetrics, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510620, PR China.
Postgraduate medical journal
|July 10, 2023
概括
在心力衰竭的异常心电图 (ECG) 预测了更糟糕的结果,包括心血管死亡和HF住院治疗. 医生应该仔细评估HFpEF患者的心电图发现,以获得预后见解.
科学领域:
- 心脏病学 心脏病学
- 临床医学 临床医学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 电心电图 (ECG) 经常用于心力衰竭与保存喷射率 (HFpEF) 管理.
- 在HFpEF中异常心电图发现的预后影响尚未完全确定.
- 之前对HFpEF中ECG预后标志物的研究往往具有有限的样本大小.
研究的目的:
- 为了研究基线异常心电图 (ECG) 的预后值,在心力衰竭患者中,保留喷射分数 (HFpEF).
- 利用大规模TOPCAT试验的数据来评估ECG在HFpEF中对心血管不良事件的预测能力.
- 在这个患者群体中确定与预后不佳相关的特定心电图异常.
主要方法:
- 对来自TOPCAT-美洲队列的1736名心力衰竭患者的分析,其中包括保存的喷射分数 (HFpEF).
- 根据正常与异常的基线心电图 (ECG) 发现,患者被分为两类.
- 对主要复合终点 (心血管死亡,HF住院,心脏骤停),所有原因死亡,心血管死亡和HF住院) 进行了生存分析.
主要成果:
- 在HFpEF患者中,异常心电图显著与初级终点 (HR:1.480) 和高压住院 (HR:1.400) 的风险增加有关.
- 捆绑分支块预测了主要终点和HF住院,而心房动/动与所有原因和心血管死亡有关.
- 非指定的心电图异常也与初级终点的更高风险相关 (HR: 1.213).
结论:
- 基线异常心电图 (ECG) 与心力衰竭患者的预后较差,心力衰竭患者的预后较差,心力衰竭患者的预后较差.
- 特定的心电图发现,如捆绑分支阻塞和心房动,具有明显的预后影响.
- 临床医生应将HFpEF患者的异常心电图发现视为不良结果的显著指标.
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