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末期肝病和肝移植后的肉类
S Leunis1, M Vandecruys2, A H Van Craenenbroeck2
1Department of Microbiology, Immunology and Transplantation, Abdominal Transplantation, KU Leuven, Leuven, Belgium.
Acta gastro-enterologica Belgica
|July 10, 2023
概括
在肝脏疾病患者中常见的萨尔科佩尼亚会对移植结果产生负面影响. 管理需要多模式的方法,包括运动和营养,因为移植往往无法逆转肌肉损失.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 老年病的医生 老年病的医生
- 肌肉生理学 肌肉生理学
背景情况:
- 麻症影响30-70%的末期肝病 (ESLD) 患者.
- 它与不良结果有关,包括延长恢复,感染和肝移植后死亡率.
- 多因素的原因包括高氨血症,低BCAA,低丸激素,炎症,营养不良和不活动.
研究的目的:
- 审查ESLD患者肉症的定义,评估和管理.
- 在肝移植前和之后的背景下讨论肉类症.
- 突出目前和新兴的治疗策略.
主要方法:
- 现有文献的叙述性审查.
- 专注于肌肉质量,力量和功能的诊断标准和评估工具.
- 综合现有和研究中的治疗选择.
主要成果:
- 麻症显著恶化了肝移植前后的结果.
- 肝移植经常无法逆转肉类,并且可以出现新的肉类.
- 评估需要成像,动力测量和物理性能测试.
结论:
- 麻症是ESLD影响移植成功的关键并发症.
- 建议采用多模式治疗,将运动和营养结合起来.
- 药理学剂正在为未来的疗法进行研究.
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