双边威尔姆斯瘤中的脏计分系统:预测性应用
Pengfei Gao1,2, Hong Jiang2, Chenglin Wu1
1Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Pediatric surgery international
|July 10, 2023
概括
脏 nefrometry 评分系统有助于评估双边威尔姆斯瘤 (BWT) 的复杂性. 虽然没有直接预测预后,但它指导治疗,低复杂度瘤适合脏节约手术 (NSS),高复杂度瘤受益于脏自移植.
科学领域:
- 儿科瘤学 儿科瘤学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 手术瘤学手术瘤学
背景情况:
- 双边威尔姆斯瘤 (BWT) 提出了独特的外科手术挑战.
- 准确评估瘤特征对于治疗规划至关重要.
研究的目的:
- 评估RENAL脏计分系统在表征双边威尔姆斯瘤中的适用性.
- 为了将瘤复杂性与手术管理和患者的结果相关联.
主要方法:
- 从2010-2022年对29名BWT患者 (53个脏单位) 的回顾性审查.
- 独立评估瘤复杂性使用RENAL评分的盲目审查者.
- 瘤特征与手术干预 (脏节约手术与彻底切除术) 的比较和结果.
主要成果:
- 大多数BWT具有高度复杂性 (60.4%),其中很大一部分具有多重病变 (26.4%).
- 脏节约手术 (NSS) 在79.2%的脏单位中进行,复杂性较低的瘤倾向于NSS.
- 脏自移植用于接受NSS.的复杂度较高的瘤.
结论:
- 脏分数有效地描述了BWT的解剖复杂性.
- 虽然复杂性与这个队列的预后没有相关性,但它决定了手术方法的选择.
- 对于低复杂性BWT来说,NSS是可行的,脏自移植为复杂病例提供了解决方案,尽管对于多焦点疾病和瘤血栓需要精细评分.
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