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Updated: Jul 24, 2025

High Precision FRET at Single-molecule Level for Biomolecule Structure Determination
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ALX/FPR2 激活 D1 溶解素的立体异构体,通过分子动力学模拟进行解

Vinicius S Nunes1,2, Odonírio Abrahão2, Alexandre P Rogério3

  • 1Laboratório Nacional de Computação Científica, Petrópolis, Rio de Janeiro, 25651-076, Brasil.

The journal of physical chemistry. B
|July 10, 2023
PubMed
概括

瑞索尔D1 (RvD1) 和阿司匹林触发的RvD1 (AT-RvD1) 通过ALX/FPR2受体解决炎症. 与AT-RvD1相比,RvD1保持了受体在活性状态的时间更长,突出了药物开发的关键相互作用部位.

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